Comparative Responsiveness of Hypothyroxinemia and Hepatic Enzyme Induction in Long-Evans Rats Versus C57BL/6J Mice Exposed to TCDD-like and Phenobarbital-like Polychlorinated Biphenyl Congeners
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چکیده
منابع مشابه
Polychlorinated biphenyl effects on avian hepatic enzyme induction and thyroid function.
Polychlorinated biphenyls (PCBs) decrease thyroid function in laboratory rodents by inducing activity of a liver enzyme, uridine diphosphate-glucuronosyltransferase (UDP-GT), thereby increasing thyroxine (T4) clearance. This loss of T4 can lead to hypothyroidism. In this study, an assay was validated for measuring UDP-GT activity toward T4 in Japanese quail. UDP-GT induction by Aroclor 1254 was...
متن کاملtragic contradictions: a comparative study of characterization in eugene o’neill’s long day’s journey into night and mahmud dowlatabadi’s tangna
در طی چند دهه ی اخیر، مفهوم «تراژدی» و «قهرمان تراژدی» توجهی روزافرون را تقریباً در تمام حوزه های نقد ادبی به خود معطوف کرده است. برخی نظیر ارسطو، نیچه، و آرتور میلر به بازخوانی آن پرداخته و برخی دیگر نظیر سارتر، استریندبرگ، یوجین اُنیل، برتولت برشت، و آنتونین آرتود به افزودن ابعاد نوینی به این مبحث همت گماشته اند. آنچه قهرمان تراژدی مدرن را از مفهوم کلاسیک آن متمایز می کند نه لغزش تراژیک متداول ...
the comparative impact of prompts and recasts in processing instruction versus meaningful output-based instruction on efl learners’ writing accuracy
the purpose of the present study was to see which one of the two instruction-processing instruction (pi) and meaningful output based instruction (mobi) accompanied with prompt and recast- is more effective on efl learners’ writing accuracy. in order to homogenize the participants in term of language proficiency a preliminary english test (pet) was administrated between 74 intermediate students ...
Concentrations and Profiles of Polychlorinated Naphthalene Congeners in Eighteen Technical Polychlorinated Biphenyl Preparations
Concentrations and profiles of trithrough octa-chlorosubstituted polychlorinated naphthalene (PCN) congeners were determined in eighteen technical polychlorinated biphenyl (PCB) mixtures including Aroclors, Kanechlors, Clophens, Phenoclors, Sovol, and Chlorofen. PCNs were found in all the PCB mixtures at concentrations ranging from 5.2 to 730 μg/g. Concentrations of PCNs in Aroclor and Kanechlo...
متن کاملBehavioural hyperactivity in rats following postnatal exposure to sub-toxic doses of polychlorinated biphenyl congeners 153 and 126.
Rats were exposed through mother's milk either to the di-ortho-substituted polychlorinated biphenyl (PCB) congener 2,2',4,4',5,5'-CB (IUPAC no. 153) or to the non-ortho-substituted PCB congener 3,3',4,4',5-CB (IUPAC no. 126). The different groups of mothers were dosed via gavage with corn oil vehicle, 5 mg/kg b.w. of PCB 153 or 2 microg/kg b.w. of PCB 126 every second day from day 3 to 13 after...
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ژورنال
عنوان ژورنال: Toxicological Sciences
سال: 2002
ISSN: 1096-0929
DOI: 10.1093/toxsci/68.2.372